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Drug: Aceclofenac 100mg + Tizanidine 2mg | Class: NSAID + Muscle Relaxant Combination | Brand: Zerodol MR (Ipca); Aceclo Plus TZ | Indication: Musculoskeletal pain with spasm, back pain, neck pain, post-operative pain | Dose: 1 tablet twice daily with food
Aceclofenac-Tizanidine is used for musculoskeletal pain with spasm, back pain, neck pain, post-operative pain.
Aceclofenac-Tizanidine contains Aceclofenac 100mg + Tizanidine 2mg, a nsaid + muscle relaxant combination for musculoskeletal pain with spasm, back pain, neck pain, post-operative pain. BNF/NICE/ACR evidence-based analgesic.
| Attribute | Details |
|---|---|
| Generic Name | Aceclofenac 100mg + Tizanidine 2mg |
| Drug Class | NSAID + Muscle Relaxant Combination |
| Brand Reference | Hifenac-TZ (Intas India); Aceclo Plus TZ |
| Indication | Musculoskeletal pain with spasm, back pain, neck pain, post-operative pain |
| Standard Dose | 1 tablet twice daily with food. Tizanidine adds muscle relaxant action to NSAID anti-inflammatory effect. Max 2 tablets/day |
| Form | Tablet |
| Route | Oral |
| Prescription | Yes |
| Evidence | BNF/NICE/ACR evidence-based analgesic |
COX enzyme inhibition reducing prostaglandin synthesis and inflammation.
All oral NSAIDs should be taken with food or milk to reduce gastric irritation. Topical formulations apply directly to skin without food restrictions.
NSAIDs can cause gastric ulceration, bleeding, and perforation — risk increases with age, concurrent steroids, anticoagulants, or H. pylori. A PPI (omeprazole, pantoprazole) should be co-prescribed for patients over 65 or with additional GI risk factors.
NSAIDs cause sodium retention and vasoconstriction, raising blood pressure in susceptible patients — particularly problematic in hypertensive patients on ACE inhibitors or ARBs. Blood pressure should be monitored and NSAID use minimised in hypertensive patients.
NSAIDs should be used at the lowest effective dose for the shortest duration. Short-term (1–2 weeks) for acute pain is generally safe; long-term use for arthritis requires regular review of GI, cardiovascular, and renal risk.
NSAIDs combined with anticoagulants (warfarin, aspirin, clopidogrel) significantly increase bleeding risk. This combination should only be used if clinically essential with enhanced GI protection (PPI) and bleeding monitoring.
Store at 15–30°C away from sunlight and moisture. Keep out of reach of children.
Orders ship from our India Head Office within 1–2 business days of confirmation. We include full customs documentation — HS codes, certificates of origin, and pharmaceutical export permits.
Estimated delivery: 3–7 business days to UK. 7–10 business days to UAE, Saudi Arabia and Gulf countries. 10–15 days for USA and Asian countries.
All packages arrive in plain, unmarked brown boxes. No pharmacy name or medication details on the outside.
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