Yohimbine 5mg Tablet

Yohimbine Hydrochloride 5mg Tablets

Alpha-2 Adrenergic Receptor Antagonist

Last Updated: June 27, 2026
Medical Review Status: Reviewed for scientific accuracy
Reviewed By: Pharmaceutical Affairs Team
Reading Time: 6 min read

Quick Facts

Quick Answer

Yohimbine Hydrochloride 5 mg is an alpha-2 adrenergic receptor antagonist that increases sympathetic nervous system activity by blocking presynaptic alpha-2 receptors. It has historically been prescribed in certain countries for selected cases of erectile dysfunction and has also been investigated in clinical research involving sexual health, vascular function, metabolism, and autonomic nervous system regulation. Regulatory approval and clinical use vary between countries.

Why is Yohimbine Different?

• Selective alpha-2 adrenergic receptor antagonist
• Orally administered tablet formulation
• Acts through central and peripheral adrenergic pathways
• Historically studied for erectile dysfunction and vascular function
• Investigated in metabolic and autonomic nervous system research
• Regulatory status differs across international markets

Product Overview

Yohimbine Hydrochloride 5 mg Tablets contain a purified pharmaceutical form of yohimbine, an indole alkaloid originally isolated from the bark of the Pausinystalia yohimbe tree. Unlike herbal yohimbe supplements, pharmaceutical-grade Yohimbine Hydrochloride contains a standardized active ingredient and has been investigated in controlled clinical settings.

Yohimbine works by selectively blocking presynaptic alpha-2 adrenergic receptors, resulting in increased norepinephrine release and enhanced sympathetic nervous system activity. This pharmacological action has led to investigations involving erectile dysfunction, vascular physiology, autonomic nervous system disorders, body composition, and exercise metabolism.

Although Yohimbine has been prescribed in some countries for selected clinical indications, its regulatory approval differs worldwide. In the United States, prescription Yohimbine Hydrochloride is distinct from over-the-counter yohimbe dietary supplements, which are not standardized pharmaceutical products. Healthcare professionals should consult local prescribing information before recommending its use.

This page provides scientific and educational information regarding Yohimbine Hydrochloride and should not be interpreted as medical advice or a recommendation for treatment.

Product Information

Mechanism of Action

Yohimbine competitively blocks presynaptic alpha-2 adrenergic receptors, increasing norepinephrine release and sympathetic nervous system activity. These effects may influence vascular tone, blood flow, neurotransmission, and physiological responses mediated by adrenergic signaling.

Clinical Research Areas

• Erectile Dysfunction
• Male Sexual Health
• Autonomic Nervous System Disorders
• Orthostatic Hypotension Research
• Vascular Function
• Exercise Physiology
• Body Composition Research
• Metabolic Studies

Potential Pharmacological Effects

• Increased sympathetic nervous system activity
• Enhanced norepinephrine release
• Modulation of vascular function
• Central nervous system stimulation
• Adrenergic receptor blockade

Safety Information

Yohimbine may cause increased heart rate, elevated blood pressure, anxiety, restlessness, tremor, dizziness, insomnia, headache, nausea, and gastrointestinal discomfort. Individuals with cardiovascular disease, uncontrolled hypertension, psychiatric disorders, kidney disease, or liver impairment should consult a qualified healthcare professional before use where legally available.

Drug Interactions

Yohimbine may interact with antidepressants, antihypertensive medications, stimulant drugs, monoamine oxidase inhibitors (MAOIs), central nervous system stimulants, and medications affecting blood pressure or heart rhythm. Medical supervision is recommended.

Yohimbine 5mg Tablet

Yohimbine 5mg Tablet contains yohimbine and is supplied in a box of 100 tablets by Evolve Biolabs. Check the Yohimbine Tablet Price and order genuine Yohimbine Supplement Tablets with reliable quality and discreet packaging.

• Contains yohimbine 5mg in convenient tablet form.
• Supplied in a box of 100 tablets.
• Manufactured by Evolve Biolabs for reliable quality.
• Competitive Yohimbine Tablet Price for genuine Yohimbine 5 Mg Tablets For Men with discreet delivery.

Storage

Store below 25°C in a dry place, protected from moisture and direct sunlight. Keep out of reach of children.

Frequently Asked Questions (FAQs)

1. How does Yohimbine 5mg Tablet work?

   Yohimbine 5mg Tablet works by affecting specific receptors in the body and may improve blood flow and nerve signalling in certain clinical situations. It should only be taken exactly as prescribed by your doctor.

2. Can I take Yohimbine 5mg Tablet with other medications?

   Some medicines may interact with Yohimbine 5mg Tablet, including medications for blood pressure, depression, and certain mental health conditions. Inform your healthcare provider about all medicines and supplements you are taking.

3. Do I need a prescription to buy Yohimbine 5mg Tablet in the USA?

   Yes. In the USA, Yohimbine 5mg Tablet is a prescription-only medicine. Always follow your local regulations and your healthcare provider’s advice, and purchase only from a licensed supplier such as Drugs General.

4. How should Yohimbine 5mg Tablet be stored?

   Store Yohimbine 5mg Tablet according to the instructions on the packaging, away from moisture, heat, and direct sunlight. Keep it out of the reach of children.

5. What are the common Yohimbine 5mg Tablet side effects?

   Common Yohimbine 5mg Tablet side effects may include increased heart rate, nervousness, dizziness, headache, or difficulty sleeping. If you experience severe side effects, seek medical attention immediately.

References

1. FDA Drug Information.
2. National Institutes of Health (NIH).
3. European Medicines Agency publications.
4. Clinical pharmacology literature.
5. Peer-reviewed studies on Yohimbine Hydrochloride.

Medical Disclaimer

This information is provided for educational purposes only. Yohimbine Hydrochloride has varying regulatory approval worldwide and may not be approved for medical use in all countries. This content should not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional regarding appropriate medical care and local prescribing regulations.