Drug: Buspirone Hydrochloride | Class: Azapirone Anxiolytic — Non-Benzodiazepine | Brand: Buspar (Bristol-Myers Squibb); Anxipar (Sun Pharma India); Buspin 10 (Intas Pharma) | Indication: Generalised anxiety disorder (GAD) | Dose: 7
Quick Answer — What is Buspirone used for?
Buspirone is used for generalised anxiety disorder (gad). FDA-approved for GAD; Cochrane confirmed; unique — no sedation, no dependence, no withdrawal; not effective for acute an. Always start at the lowest dose and titrate under physician supervision.
Buspirone – Azapirone Anxiolytic — Non-Benzodiazepine
Buspirone contains Buspirone Hydrochloride, a azapirone anxiolytic — non-benzodiazepine for generalised anxiety disorder (gad). FDA-approved for GAD; Cochrane confirmed; unique — no sedation, no dependence, no withdrawal; not effective for acute anxiety.
Product Information
| Attribute |
Details |
| Generic Name |
Buspirone Hydrochloride |
| Drug Class |
Azapirone Anxiolytic — Non-Benzodiazepine |
| Brand Reference |
Buspar (Bristol-Myers Squibb); Anxipar (Sun Pharma India) |
| Indication |
Generalised anxiety disorder (GAD) |
| Standard Dose |
7.5mg twice daily initially; increase to 15mg twice daily after 2–3 days. Maximum 60mg/day. Takes 2–4 weeks for effect |
| Form |
Tablet |
| Route |
Oral |
| Prescription |
Yes |
| Evidence |
FDA-approved for GAD; Cochrane confirmed; unique — no sedation, no dependence, no withdrawal; not effective for acute anxiety |
How It Works
Partial 5-HT1A agonism reducing anxiety without sedation.
People Also Ask
How long does Buspirone take to work?
Antidepressants and anxiolytics generally require 2–4 weeks to show meaningful clinical effect. Full response may take 6–8 weeks. Do not discontinue early — premature stopping causes relapse. Buspirone specifically requires 2–4 weeks for anxiolytic effect and does not work for acute anxiety.
Can Buspirone be stopped suddenly?
Buspirone can generally be stopped without a discontinuation syndrome, unlike benzodiazepines or antidepressants.
Does Buspirone cause sexual dysfunction?
SSRIs and many TCAs cause sexual dysfunction (reduced libido, delayed orgasm) in 30–60% of patients — a major cause of non-adherence. Bupropion is uniquely associated with minimal or no sexual dysfunction. Mirtazapine, tianeptine, and agomelatine also have lower sexual dysfunction rates.
Is Buspirone addictive?
Buspirone has no addiction or dependence potential — a key advantage over benzodiazepines for long-term anxiety treatment.
Can Buspirone and alcohol be combined?
Alcohol and antidepressants/anxiolytics interact unfavourably — increased CNS depression, worsened mood, reduced efficacy. Alcohol should be minimised or avoided during treatment with any psychotropic medication.
Storage
Store at 15–30°C away from sunlight and moisture. Keep out of reach of children.
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