Buy Primidone 12.5 mg Tablets online. Each tablet contains 12.5 mg of primidone, an anticonvulsant used to control some types of epileptic seizure and to treat essential tremor. It contains the same active ingredient as the reference brand Mysoline. In the USA, UK and Australia it is a prescription medicine, so a valid prescription is needed for your order. See today’s price above and add it to your cart.
The 12.5 mg tablet is a low starting dose, used to begin treatment gently, mainly in essential tremor and in people who are sensitive to the first-dose effect. Approved uses and legal status differ between countries, so this page covers the USA, UK, Australia, the UAE and Russia.
The reference (original) brand of primidone is Mysoline, sold in the UK, USA, Australia and many other countries, usually as 50 mg and 250 mg tablets. Primidone is also sold as generic tablets and under other brand names, and lower strengths such as 12.5 mg and 25 mg are used for starting treatment in some countries.
Compare the strength, manufacturer and packaging on your product. Tablet strengths differ between countries, so check that the strength matches your prescription and never swap strengths without your prescriber’s advice.
Epilepsy: primidone is used for generalised tonic-clonic seizures and for focal (partial) seizures, alone or with other antiepileptic medicines.
Essential tremor: primidone is widely used to reduce the shaking of essential tremor, and the UK product information describes this use.
Low starting dose: the 12.5 mg strength is used as a very gentle first step, particularly in older adults and people with tremor, where the dose is raised slowly to find the lowest effective amount.
Primidone is an anticonvulsant that the body partly converts into phenobarbital. Both the original medicine and its by-products calm overactive electrical signalling in the brain, which lowers the chance of seizures. In essential tremor, it is thought to dampen the abnormal nerve activity that produces the shaking. It starts working gradually as the dose is built up.
Dosing is built up slowly and decided by your prescriber. For epilepsy, the UK product information describes starting at 125 mg at bedtime and increasing in steps over about ten days, with the total daily dose split into two or three doses. The US label describes a similar build-up, starting with 100 to 125 mg at bedtime, up to a maximum of about 2 g a day.
Low-dose starts: for essential tremor and for sensitive patients, treatment often begins with a small dose at bedtime, such as 12.5 mg, and is increased slowly over weeks. Take the tablets at the same time each day, with or without food. Always follow the leaflet in the pack and the advice of your prescriber or pharmacist.
Seek urgent medical help for thoughts of harming yourself, a severe skin rash with blisters or fever, severe drowsiness or slow breathing, swelling of the face, lips or throat, or a sudden increase in seizures. Long-term use can lower folate and vitamin D levels and, rarely, cause anaemia or bone thinning, so your doctor may check your blood.
Store the tablets in their original pack at room temperature, away from moisture and light, following any instructions on the pack. Keep out of the reach of children and do not use after the expiry date.
Ordering Primidone 12.5mg Tablets takes a few minutes:
Questions before you order? Message a pharmacist on WhatsApp or call the support line shown on this page.
What is primidone 12.5 mg used for?
Primidone is used to control some types of epileptic seizure and to treat essential tremor, according to UK product information. The 12.5 mg strength is typically used as a low starting dose for essential tremor or when beginning treatment gently. Your prescriber chooses the dose.
What is the reference brand of primidone?
The reference (original) brand is Mysoline. Primidone is also sold as generic tablets and under other brand names. Always check the strength and manufacturer on the pack you receive.
Do I need a prescription for primidone?
Yes. In the USA, UK and Australia, primidone is a prescription medicine. Upload your prescription at checkout or on the Upload prescription page, and our pharmacist will check it before dispatch.
How do I buy primidone 12.5 mg tablets online?
Choose your pack, add it to your cart and check out securely. Because a prescription is required, upload it at checkout or on the Upload prescription page. Our pharmacist checks it before dispatch, and you can follow your order from your account.
Why is primidone started at 12.5 mg?
A low starting dose reduces the first-dose effects of sleepiness and dizziness, which can be marked. The dose is then raised slowly. Starting low is especially common in essential tremor and in older adults.
How long does primidone 12.5 mg take to work for tremor?
The tremor often starts to ease over days to a few weeks as the dose is increased. The full effect may take longer, and the 12.5 mg dose is usually only the first step. Follow your prescriber’s plan.
Why does primidone make me drowsy at first?
The first doses can cause marked sleepiness and dizziness, because the body takes time to adapt. This is why treatment starts at a very low dose and is increased slowly. Avoid driving and alcohol until you know how it affects you.
Can I stop taking primidone suddenly?
No. Stopping suddenly can bring on seizures, including serious ones. Only reduce or stop primidone gradually, on your prescriber’s advice.
Does primidone affect the contraceptive pill?
Yes. Primidone can make the contraceptive pill and some other hormonal methods less effective, so extra or different contraception may be needed. Ask your doctor or pharmacist for advice.
Is primidone safe in pregnancy?
Primidone can harm an unborn baby, so it should only be used in pregnancy if your doctor decides it is clearly necessary. Do not stop it on your own, because uncontrolled seizures are also dangerous. Speak to your doctor if you are planning a pregnancy.
Which countries do you deliver to?
We deliver to the USA, UK, Australia, the UAE, Russia and many other countries. Delivery options and the estimated delivery time for your country are shown at checkout before you pay.
Can I return or cancel my order?
Orders cannot be cancelled once placed, and refunds follow our Shipping, Returns and Refunds policy. Please check your order details carefully before you confirm it.
This page provides general product information and does not replace professional medical advice, diagnosis or treatment. Primidone is a prescription medicine and must be used only as directed by your prescriber. Follow the official product information and the guidance of a healthcare professional.
Last Updated: October 28, 2026
Orders ship from our India Head Office within 1–2 business days of confirmation. We include full customs documentation — HS codes, certificates of origin, and pharmaceutical export permits.
Estimated delivery: 3–7 business days to UK. 7–10 business days to UAE, Saudi Arabia and Gulf countries. 10–15 days for USA and Asian countries.
All packages arrive in plain, unmarked brown boxes. No pharmacy name or medication details on the outside.
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.