Buy Azelaic Acid 20% Cream online. Each gram of cream contains 200 mg (20%) of azelaic acid, a topical medicine used to treat mild to moderate acne. The same strength is sold under brand names such as Skinoren and Azelex. In the UK and the USA, azelaic acid 20% cream is a prescription medicine, so a valid prescription is needed for your order. See today’s price above and add it to your cart.
Azelaic acid is applied directly to the skin, so only a small amount enters the bloodstream. It does not work overnight: improvement is usually seen after about four weeks, and treatment is often continued for several months. Approved uses and legal status differ between countries, so this page covers the USA, UK, Australia, the UAE and Russia.
Acne vulgaris: the labelled use of azelaic acid 20% cream in the UK and USA is mild to moderate acne. It helps to reduce blackheads, whiteheads and the red, inflamed spots that come with acne.
Rosacea and dark patches: doctors also use azelaic acid for rosacea and for pigmentation such as melasma. In the USA the products labelled for rosacea are a 15% gel and foam, so using the 20% cream for these conditions is a decision for your prescriber. Ask which strength suits your skin.
Azelaic acid treats the spots and marks, not the underlying tendency to acne, so it is normally used alongside a gentle skincare routine. Ask your prescriber before using it on a child.
Azelaic acid is a natural dicarboxylic acid. On the skin it has three main actions. It reduces the growth of the bacteria linked to acne, it helps unblock pores by normalising how skin cells are shed, and it calms inflammation and redness. It also slows the activity of pigment-making cells, which is why it is used for dark marks left by acne.
Wash the affected area with water or a mild cleanser and pat it dry. Apply a thin layer of cream and massage it in gently. The US label describes use twice a day, morning and evening, and your prescriber may give different directions. Wash your hands after applying. Do not cover the area with an airtight dressing.
If burning or stinging is troublesome, the US label suggests using the cream once a day until the irritation settles, then returning to twice a day. Moisturiser and cosmetics can be used once the cream has dried. Improvement is usually seen after about four weeks, and many people continue for several months. Always follow the leaflet in the pack and the advice of your prescriber or pharmacist.
Seek urgent medical help for swelling of the face, lips, tongue or throat, hives or difficulty breathing. Stop using the cream and speak to your prescriber if you develop severe irritation, blistering or worsening asthma symptoms; these have been reported with azelaic acid.
Keep the cream in its original tube with the cap closed and follow any storage instructions printed on the pack. Keep out of the reach of children and do not use after the expiry date.
Ordering Azelaic Acid 20% Cream takes a few minutes:
Questions before you order? Message a pharmacist on WhatsApp or call the support line shown on this page.
What is azelaic acid 20% cream used for?
It is used to treat mild to moderate acne, according to UK and US product information. It helps reduce blackheads, whiteheads and inflamed spots. Some prescribers also use it for rosacea or dark patches, but that goes beyond the labelled use, so ask your prescriber what is right for you.
What is the brand name of azelaic acid 20% cream?
Azelaic acid 20% cream is sold as Skinoren in the UK, Europe and several other countries, and as Azelex in the USA. The brands contain the same active ingredient at the same strength. Always check the strength and form on the pack you receive.
Is azelaic acid 20% cream available over the counter?
In the UK and USA, no. The 20% cream is a prescription medicine, and you can upload your prescription with your order for our pharmacist to check. Rules differ in other countries, and 10% azelaic acid products are often sold as skincare.
How do I buy azelaic acid 20% cream online?
Choose your pack, add it to your cart and check out securely. Because a prescription is required, upload it at checkout or on the Upload prescription page. Our pharmacist checks it before dispatch, and you can follow your order from your account.
How do I use azelaic acid 20% cream?
Wash and dry the skin, then apply a thin layer and massage it in gently, usually twice a day, morning and evening. Wash your hands afterwards and avoid the eyes and mouth. Follow the directions from your prescriber and the leaflet in the pack.
How long does azelaic acid 20% cream take to work?
Most people notice an improvement after about four weeks of regular use, and treatment is often continued for several months. Mild stinging at the start is common. Keep using it as directed and tell your prescriber if there is no improvement.
Can I use azelaic acid 20% cream for rosacea?
Azelaic acid is used in rosacea, but the products labelled for rosacea in the USA are a 15% gel and foam. A prescriber may choose the 20% cream for some patients. Ask your prescriber before using it for rosacea, and avoid the eyes.
Can azelaic acid 20% cream help with melasma or dark spots?
Azelaic acid slows the activity of pigment-making cells, and doctors use it for dark patches such as melasma and marks left by acne. This is outside the labelled acne use of the 20% cream, so use it for pigmentation only on your prescriber’s advice.
Is azelaic acid cream safe in pregnancy?
Information in pregnancy is limited, and only a small amount is absorbed through the skin. The US label advises use in pregnancy only if clearly needed. Speak to your prescriber before using azelaic acid if you are pregnant, planning a pregnancy or breastfeeding.
What is the difference between azelaic acid 10% and 20%?
The number is the percentage of azelaic acid in the product. The 20% cream is the prescription strength used to treat acne, while 10% products are usually sold as skincare and are milder. A higher strength can cause more stinging at first.
Which countries do you deliver azelaic acid to?
We deliver to the USA, UK, Australia, the UAE, Russia and many other countries. Delivery options and the estimated delivery time for your country are shown at checkout before you pay. A valid prescription is still required for this cream.
Can I return or cancel my order?
Orders cannot be cancelled once placed, and refunds follow our Shipping, Returns and Refunds policy. Please check your order and prescription details carefully before you confirm it.
This page provides general product information and does not replace professional medical advice, diagnosis or treatment. Azelaic acid 20% cream is a prescription medicine and should be used only as directed by your prescriber. Follow the official product information and the guidance of a healthcare professional.
Last Updated: October 28, 2026
Orders ship from our India Head Office within 1–2 business days of confirmation. We include full customs documentation — HS codes, certificates of origin, and pharmaceutical export permits.
Estimated delivery: 3–7 business days to UK. 7–10 business days to UAE, Saudi Arabia and Gulf countries. 10–15 days for USA and Asian countries.
All packages arrive in plain, unmarked brown boxes. No pharmacy name or medication details on the outside.
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